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Orthopedics & Pain Management

Regenerative Orthopedics

These advanced treatments use cutting-edge stem cell–based therapies to support joint repair, reduce inflammation, and improve mobility. The goal is to slow disease progression, enhance tissue healing, and in many cases delay or help avoid surgical intervention.

Eligibility Framing

Focused on Joint Function and Longevity

Eligibility for regenerative joint therapies is determined following a comprehensive medical assessment. As part of this process, patients undergo baseline diagnostic evaluations and targeted imaging to help determine clinical suitability and establish personalized treatment benchmarks. These assessments allow our medical team to evaluate joint health, levels of inflammation, and the potential for tissue repair before recommending any intervention.

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Who May Benefit
These regenerative therapies are designed to support long-term mobility, reduce discomfort, and enhance overall joint health.
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What it supports
These regenerative joint therapies support the body’s natural healing processes, helping to reduce inflammation, promote tissue repair, and improve overall joint function. They are designed to enhance mobility, relieve discomfort, and maintain long-term joint health, while in many cases helping to delay or avoid the need for surgical intervention.
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Safety, Oversight and Responsibilty
All regenerative joint treatments are conducted under strict medical supervision by our experienced clinical team. Each protocol is carefully planned and monitored to ensure patient safety, with ongoing assessments to track progress and adjust treatment as needed. Our approach prioritizes clinical responsibility, evidence-based practices, and the highest standards of care to support both effective outcomes and long-term joint health.
RMI APPROACH

A sequenced biological protocol

The 3-Step
Regenerative Protocol - A physician-guided, multi-day clinical process designed to reduce inflammatory burden and support the body’s regenerative signaling.

1

Plasma exchange

After medical consultation and bloodwork, patients arrive for intake and vitals. Therapeutic Plasma Exchange (TPE) removes inflammatory substances. Duration: 2–3 hours.

2

Clinical review & program design

Every patient begins with a physician-led review of medical history, labs, and goals. This consultation helps determine suitability and allows the care team to tailor the protocol to individual needs.

3

Cellular infusion

Expanded MSCs are administered intravenously, followed by MUSE cells. This sequence primes the biological terrain for optimal cell retention. Nutritional IV included.

RMI EXPERIENCE

Designed for clarity, privacy, and continuity.

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Explore

Eligibilty Review

A detailed consultation to understand your health history, clarify expectations, and define realistic, long‑term goals for treatment and recovery.

Medical Onboarding

You meet with an RMI physician to review your needs, confirm eligibility, and determine any testing required before treatment.

Treatment & Care

Within our state-of-the-art facility, regenerative therapies are delivered by experienced physicians in a quiet, closely supervised setting.

Privacy & Trust

Every interaction, consultation, and record is handled with care, ensuring that your data remains private and protected.

Concierge Experience

Everything around your stay is privately coordinated with the medical team, so your energy goes toward preparation, treatment, and recovery.

Ongoing Guidance

Scheduled check‑ins and virtual consultations keep your progress on track and your mind at ease, following your departure

TESTIMONIALS

“RMI stands out to me for two reasons: they’re operating at the cutting edge of what’s currently possible with regenerative medicine, and they’re backed by some of the most experienced and trustworthy longevity physicians in the world.”

Bio-Hacker | 4x NYT Author

Dave Asprey

“What I appreciate about RMI is that it aligns with how I think about health
professionally: proactive, science-driven, individualized, and focused on the long game. I’m not here for a quick fix. I’m here because I want to be functional, clear-headed, and capable for as long as possible. That’s what good medicine should be working toward — and that’s what I’ve found here.”

Epidemiologist | U.S. Army Veteran

Chris Lindley

“I came to RMI and gave it a shot. A few weeks later, I felt brand new. That’s not
something I say lightly — I don’t really believe in much — but what happened here was
real. I woke up feeling well-rested, like a different person.”

UFC Heavyweight Fighter

Derrick Lewis

“I’ve referred astronauts here. Several have come through, and every one of them has had
a positive experience. I’ve also gone through a number of their therapies personally,
which is why my trust in this team isn’t just professional — it’s personal. I wouldn’t send
my astronauts somewhere I hadn’t vetted myself.”

Retired Flight Surgeon for NASA

Smith Johnston

“What truly sets RMI apart is not any single treatment, but the way
everything is thoughtfully integrated into a personalized, science-driven approach to
long-term health and well-being. The team combines world-class expertise with genuine
humanity- you are listened to, educated, and supported at every step. The impact on my
energy, clarity, physical comfort, and overall sense of well-being has been profound.”

Author, Social Entrepreneur

Marc Kielberge

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The longevity experience for those who demand more - designed to keep you sharp, mobile, and resilient.

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Disclaimer – RMI Health is a longevity and regenerative medicine clinic that provides advanced, medically supervised stem cell and related therapies under license from the Costa Rican Ministry of Health. All treatments are subject to eligibility criteria and are only recommended after a full clinical review by qualified physicians, which may include medical history, diagnostic testing, and consultation with your existing care team. Outcomes vary between individuals and depend on many factors—including diagnosis, overall health, and adherence to medical guidance—so no specific result, degree of improvement, or duration of benefit can be promised or guaranteed. As with any medical procedure, regenerative and stem cell therapies carry potential risks, side effects, and limitations, which will be discussed with you in advance to support informed decision‑making; RMI encourages patients to seek independent medical advice when needed and to consult insurers regarding coverage, as many longevity and regenerative treatments may be considered elective or investigational.​

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